Viro Perspectives

Learn more on the topic of Varicella Zoster Virus (VZV) via our ongoing series of clinical posts by David Kilpatrick, PhD and Abbas Vafai, PhD.

Detection of HHV-8 Associated with Kaposi’s Sarcoma

INTRODUCTION: Human herpesvirus-8 (HHV-8) is a γ-herpesvirus which is related to the Epstein-Barr virus and is etiologically associated with Kaposi’s sarcoma (KS). The AIDS epidemic over the last 40 years has resulted in a high rate of KS due to immunosuppression. The seroprevalence for HHV-8 varies from 1-5% in the US to up to 80% […]

INTRODUCTION: Human Herpes Simplex Type 2 (HSV-2) causes a life-long infection and occurs in over 10% of adult individuals. This report details the approach by Goux et al. (2019) to identify HSV-2  infections using a Smartphone to detect the nanophosphor signal of a lateral flow device. DISCUSSION: Lateral flow assays (LFAs) are needed to improve […]

INTRODUCTION: The detection of a single analyte in a lateral flow assay or lateral flow device (LFD) is a common, low cost, rapid diagnostic assay. There is, however, a need to detect more than one analyte in a single assay to further reduce the costs and time involved in the detection of multiple analytes. A […]