Viro Perspectives
Learn more on the topic of Varicella Zoster Virus (VZV) via our ongoing series of clinical posts by David Kilpatrick, PhD and Abbas Vafai, PhD.
INTRODUCTION: Reactivation of varicella-zoster virus (VZV) after a primary infection (chickenpox) leads to herpes zoster (HZ-shingles). In Part I, we discussed a review by Kennedy et al1., which looked at some recent issues in Alphaherpesvirus latency, particularly in regards to VZV ganglionic latency. In Part II, we will look at the immunological aspects of Alphaherpesviruses […]
INTRODUCTION: Reactivation of varicella-zoster virus (VZV) after a primary infection (chickenpox) leads to herpes zoster (HZ-shingles). In this review by Kennedy et al1., look at some recent issues in alphaherpesvirus latency, particularly in regards to VZV ganglionic latency. The key question they ask is the nature and extent of viral gene transcription during viral latency. […]
INTRODUCTION: Varicella-zoster virus (VZV) is a highly contagious Herpesvirus which causes chickenpox (primary infection) or shingles (upon reactivation). VZV poses a nosocomial infection for healthcare workers and patients. The incubation period for the virus is between 10-21 days. It is generally thought that patients are infectious 1-2 days prior to rash onset and between 4-7 […]