Viro Perspectives

Learn more on the topic of Varicella Zoster Virus (VZV) via our ongoing series of clinical posts by David Kilpatrick, PhD and Abbas Vafai, PhD.

INTRODUCTION: In Parts I & II we presented background on the involvement of varicella zoster virus (VZV) with the enteric nervous system (ENS). The conclusion of our three-part series will outline the diagnostic approaches to detect VZV reactivations without the external signs of shingles (Zoster sine herpete-ZSH) as outlined by Zhou et al1. DISCUSSION: The […]

INTRODUCTION: In Part I we presented background on the involvement of varicella zoster virus (VZV) with the enteric nervous system (ENS). That included evidence that reactivation of VZV within the ENS can infect gastrointestinal (GI) targets and cause enteric zoster. DISCUSSION: Zhou et al.1, present a review detailing the involvement of VZV with the enteric […]

INTRODUCTION: It is well known that varicella zoster virus (VZV) infects and becomes latent in neurons in ganglia of the cranial nerves and dorsal roots and upon reactivation leads to zoster (shingles). However, there are also ganglia associated with the enteric nervous system (ENS). Reactivation of VZV within the ENS can infect gastrointestinal (GI) targets […]