Viro Perspectives

Learn more on the topic of Varicella Zoster Virus (VZV) via our ongoing series of clinical posts by David Kilpatrick, PhD and Abbas Vafai, PhD.

INTRODUCTION: In the last several years there has been an increasing demand for the development of infectious disease diagnostics which maintains test accuracy while reducing the time needed for detection at the point-of-care (POC) for the patient. Reducing the cost per assay as well as the equipment and end-user technical knowledge has been the driving […]

By David Kilpatrick, PhD and Abbas Vafai, PhD INTRODUCTION: The detection and differentiation of HSV-1 & -2 infections present challenges in a hospital point of care environment. There are many laboratory tests which can be performed, including serological assays, polymerase chain reactions, as well as virus neutralization and/or culture. However, only simple, quick serological assays, […]

By David Kilpatrick, PhD and Abbas Vafai, PhD INTRODUCTION: Various assays have been developed over the last thirty years for detecting Herpes virus antibodies in patient sera. The three most commonly used assays are Western blot assay (WBA), enzyme-linked immunosorbent assay (ELISA), and enzyme immnodot assays (EIA). Of these, the Western blot assay (WBA) is […]