Viro Perspectives

Learn more on the topic of Varicella Zoster Virus (VZV) via our ongoing series of clinical posts by David Kilpatrick, PhD and Abbas Vafai, PhD.

Shingles vaccine adminstration

INTRODUCTION: Surprisingly, much of the general public do not know one of the human Herpesviruses, varicellazoster virus (VZV), causes chickenpox, and results in a life-long infection. VZV can re-activate after decades of being dormant in sensory nerve ganglia (usually in those over 60 years of age) to cause shingles infection.

INTRODUCTION: Herpes zoster (HZ) reactivation is characterized as a vascular rash of unilateral distribution that can also cause complications such as post-herpetic neuralgia, ophthalmic zoster, and other neurological diseases. Emerging epidemiological and clinical data recognizes an association between HZ and subsequent acute strokes and myocardial infarction (MI).